To say a random quote, type:

/srq setname CHANNEL

Where setname is the name of a quotation set you've created and CHANNEL is the CAPITALIZED name of a default channel (GUILD, YELL, SAY, PARTY, RAID, etc).  If you do not provide a CHANNEL, SAY will be used.  There is no custom channel support (yet?).

A quoteset with some quotes has been included in the addon, but creating your own is super easy.  Simply open SayRandomQuote.lua in a plain text editor such as Notepad and create a new set as below:

srq_quotes["setname"] = {
"Your quotation goes here.",
"Another quotation.",
"Make sure your lines end with commas after the end quotation mark.",
}

To use these in a macro, simply include the slash command before or after the spells/items in your macro.  The speech will fire at the same time as the item/spell:

#showtooltip
/srq random PARTY
/cast Prayer of Fortitude